BL/CH401 Biochemistry I -- Fall 1999

Short Form of this Schedule for 1999: PDF File for Printing

Professor Wilbur H. (Bill) Campbell

Office 409 Dow/ESE, 487-2214

EMAIL: wcampbel@mtu.edu

Click to View: New Protein 3-D Structure

Office Hours: Noon to 2 PM Mon, Tues, Wed, Fri

OR --- MAKE AN APPOINTMENT / LEAVE ME A MESSAGE/SEND AN EMAIL

TEXT: Principles of Biochemistry by Zubay, Parson & Vance

Lecture: MON/WED/FRI. 3:00 PM Go To Advice on BL/CH401 for Fall 1999

LECTURE SCHEDULE with READING in TEXT

Part I : Introduction to Protein Structure

1. Sept 8 Introduction Chap. 1 & 2

2. Sept 10 Cellular Structures Chap. 1 -- Download PDF File for Easier Printing: Lec 2 Cell Structure

3. Sept 13 Acids, Bases and Buffers Chap. 3 -- PDF File for Printing: Lec 3 Acid-Base

Handout: Summary of Lecture 3 -- Included in Lec 3 PDF File

4. Sept 15 Amino Acid Structures Chap. 3 -- PDF File for Printing: Lec 4 Amino Acids

5. Sept 17 Protein Covalent Structure Chap. 3 -- PDF File for Printing: Lec 5 Primary Structure

Handout: Summary of Amino Acid Sequencing Methods -- Included in Lec 5 PDF File

Problem Set #1: Amino Acid Sequence Problems -- PDF File for Printing: AA Seq Problems

Extra Problems on Using pK and finding pI -- Included in Lec 3 PDF File

6. Sept 20 Protein Purification I Chap. 6 -- PDF File for Printing: Lec 6 Proteins I

7. Sept 22 Protein Purification II Chap. 6 -- PDF File for Printing: Lec 7 Proteins II

Handout: Summary of Protein Purification Lectures -- PDF File for Printing: Protein Purification

GO TO SPECIAL: PURIFICATION TRICKS FOR RECOMBINANT PROTEINS

Sept 24 Amino Acid Sequencing -- In Class Solving of Amino Acid Sequence Problems

Answers to Problem Set #1 (posted after class) PDF File for Printing: AA Seq Answers

Sept 26 Summary Part I and Review

Sept 29 EXAM I -- 1 HOUR EXAM

Scoop: Old Exams #1****1995 Exam I with anwsers****1996 Exam I with answers **** 1997 Exam 1 along with Answers-- PDF File for Printing: Old Exams I

Oct 1 **** No Class -- Homecoming ****

Part II: Protein Structure and Enzyme Kinetics

Oct 3 Enzyme Structure and Computer Modeling (no reading) -- NO NOTES - IN CLASS DEMO

PROTEIN COMPUTER GRAPHICS -- USING MAGE & RASMOL -- DEMO FILES AND PROGRAMS AVAILABLE ON REQUEST

8. Oct 6 Protein Secondary Structure Chap. 4 -- PDF File for Printing: Lecture 8

9. Oct 8 Protein Tertiary Structure Chap. 4 -- PDF File for Printing: Lecture 9

10. Oct 11 Protein Folding and Evolution Chap. 4 -- PDF File for Printing: Lecture 10

11. Oct 13 Introduction to Enzymes Chap. 7 -- PDF File for Printing: Lecture 11

SPECIAL: Enzymes as Nano-Engines This is a PDF File for both viewing and printing

12. Oct 15 Enzyme Kinetics Chap. 7 -- PDF File for Printing: Lecture 12

13. Oct 18 Enzyme Inhibition Chap. 7 -- PDF File for Printing: Lecture 13

Oct 20 Enzyme Kinetics Problem Solving Handout -- PDF File for Printing: Problems

Answers to Enzyme Kinetics Problems (posted after class) -- PDF File for Printing: Enzyme Kinetics Answers

14. Oct 22 Hemoglobin, Allosteric Enzymes and Regulation of Enzyme Activity Chap. 5, 9 & 10 -- PDF File for Printing: Lecture 14

Oct 24 Summary Part II and Review

Oct 27 EXAM II -- 1 Hour Exam

Scoop: Old Exams #2; 1995 Exam #2; Answers to 1995 Exam #2; Answers to 1996 Exam II; Answers 1997 Exam II -- PDF File for Printing: SCOOP

Part III: Enzyme Catalysis and Regulation

Oct 29 - Enzyme Structure Computer Modeling Demo

15A. Nov 1 Enzyme Catalysis - Introduction Chap. 8 -- PDF File for Printing: Lecture 15A

15B. Nov 3 Enzyme Catalysis - Mechanisms Chap. 8 -- PDF File for Printing: Lecture 15B

15B. Addendum to Nov 3 Lecture -- PDF File for Viewing and Printing: Lec 15B Add-in

16A. Nov 5 Enzyme Catalysis - Examples Chap. 8 -- PDF File for Printing: Lecture 16A

16B. Nov 8 Enzyme Catalysis - Examples Chap. 8 -- PDF File for Printing: Lecture 16B

17. Nov 10 Protein Engineering and Transition State Theory of Enzyme Catalysis -- PDF File for Printing: Lecture 17

Nov 12 Review for the Final Exam